Watch Sunderland V Reading Live Stream Online Free HD Video On Sopcast, Sunderland V Reading Live Streaming HD Video Internet TV Sunderland's leading scorer Steven Fletcher is a doubt with the ankle injury that caused him to miss Saturday's defeat by Chelsea.
Connor Wickham will continue to deputise if Fletcher isn't fit.
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Sean Morrison could be Reading's latest absentee, having suffered an ankle injury in the defeat at Southampton.
Pavel Pogrebnyak is also a major doubt and Chris Gunter (hamstring), Jimmy Kebe (groin) and Jem Karacan (knee) are definitely out.
This fixture marks the anniversary of Martin O'Neill's first match as Sunderland manager, and the Ulsterman knows he cannot rely on a season of goodwill to keep him in the job.
Saturday's defeat by Chelsea ensured Sunderland slipped into the relegation zone in 18th place, exactly where they were prior to O'Neill's first game in charge, a 2-1 win over Blackburn. He is the bookmakers' favourite to be the next Premier League managerial casualty; victory in this re-arranged fixture against fellow strugglers Reading is a must.
How everyone connected with Sunderland must yearn for a repeat of O'Neill's initial impact at the club. His first 10 league fixtures yielded seven wins and a return of 22 points from a possible 30; the last 29 games have resulted in just four wins and 25 points. O'Neill acknowledges the significance of Tuesday's fixture: "It is a big game, but it always was going to be that. If we actually win the game, we lift ourselves into 15th position in the league.